PHLORIDZIN
FROM APPLEJACK · the apple polyphenol
The apple-skin polyphenol, the molecule that gives hard cider its astringent backbone and tannic structure. Concentrated in skin and core, so cider pressed from whole apples carries far more than juice made from peeled fruit. Pharmacologically interesting too: phloridzin blocks intestinal glucose absorption, which is the mechanism modern SGLT2-inhibitor diabetes drugs took their inspiration from.
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